What if weight loss
was never about
willpower?

For most of medical history, hunger was framed as a moral failing — willpower applied to a stubborn body.

Lose up to 22.5% of body weight in 72 weeks.*

*SURMOUNT-1 trial, tirzepatide 15 mg, NEJM 2022. NDP supplies the research-grade compounds.

NDP+ Semaglutide 5 mg — lyophilized research peptide vial
−14.9%
Mean body-weight reduction observed in STEP 1 (semaglutide, 68 weeks).Wilding et al., NEJM 2021
−22.5%
Mean body-weight reduction observed in SURMOUNT-1 (tirzepatide, 72 weeks).Jastreboff et al., NEJM 2022
21,000+
Patients enrolled across the landmark GLP-1 receptor trials of the past decade.
1,800+
Peer-reviewed papers on GLP-1 receptor pathways — new ones almost weekly.
What the science is showing

Your body wasn't
broken.
It was waiting.

For most of medical history, hunger was framed as a moral failing. Push back from the table. Walk it off. The advice was the same for fifty years and the science behind it — was wrong.

The body had been making GLP-1 all along. A class of peptides quietly orchestrating the conversation between gut and brain about appetite, satiety, and glucose. When research learned to read that signal, the published findings reshaped endocrinology in real time: a 14.9% mean body-weight reduction in the STEP 1 trial, 22.5% in SURMOUNT-1. Outcomes no behavioural intervention has ever matched, observed across more than 21,000 patients.

NDP exists for the labs continuing that work. We make the peptides. The science writes the rest.

What the body has been quietly doing all along.

01 / Appetite
Hunger, quieted.
GLP-1 research has explored how appetite signalling between gut and brain can be modulated. The findings are quietly reshaping how endocrinology thinks about food and the body.
02 / Satiety
Fullness, that lasts.
Studies have observed prolonged satiety following GLP-1 receptor activation — satiety mechanisms that last hours, not minutes. A finding now central to metabolic research.
03 / Glucose
Sugar, steadier.
Twenty years of evidence on how GLP-1 pathways shape the body's blood-sugar rhythms — a response system more responsive than earlier frameworks could explain.
04 / Food noise
Less food noise.
The phenomenon clinicians began naming when patients in GLP-1 studies described it: less mental chatter about food. The literature is now exploring exactly that mechanism.
What's behind the vial

Process, not theatre.

01 HPLC purity verification Every batch is sampled and sent to an external NATA-accredited laboratory for HPLC and mass-spec verification. Results are filed against the lot number and made available on request.
02 Endotoxin testing LAL kinetic-turbidimetric endotoxin testing per batch, with results held to research-grade thresholds. Documented on the Certificate of Analysis, sent on request.
03 Lyophilisation control Free-flowing white-to-cream powder. Sterile-filtered and packed into amber glass vials. Stored at 2–8°C.
04 Cold-chain dispatch Royal Mail Tracked 24 from our UK lab. Orders placed before 16:00 are dispatched the same business day.
Common questions

Asked often.

What does "research use only" actually mean?

Our compounds are sold and supplied for laboratory and academic research. Not for human or veterinary use. Buyers confirm RUO status at checkout.

What does the research actually show about weight?

In the major published trials, GLP-1 receptor agonists have produced mean body-weight reductions far beyond what behavioural intervention alone has ever achieved — 14.9% in STEP 1 (semaglutide, NEJM 2021) and 22.5% in SURMOUNT-1 (tirzepatide, NEJM 2022). Combined enrolment across the landmark trials exceeds 21,000 patients. NDP makes the research-grade compounds for the labs continuing that work.

Do I get a Certificate of Analysis?

Yes — on request. Email us with your lot number and we'll send the Certificate of Analysis covering batch, date, HPLC purity, mass-spec confirmation, and endotoxin reading. Historical CoAs by lot number are available the same way.

How are these different from a prescription?

Pharmacy-dispensed semaglutide is the same molecule but compounded for human therapeutic use, supplied with a prescription, dosing protocol, and clinical oversight. NDP supplies research-grade compounds, sold to labs and researchers, with a Certificate of Analysis instead of a prescription. The chemistry overlaps; the use case and supply chain do not.

Storage and stability?

Sealed vials store at 2–8°C for up to 24 months. Once reconstituted, store at 2–8°C and use within the period stated on your CoA. Avoid repeated freeze-thaw cycles.